Ozone: A powerful weapon to combat COVID-19 outbreak
By Zhou Muzhi, professor of Tokyo Keizai University and president of Cloud River Urban Research Institute.China.org.cn, February 26, 2020
For more than 100 years, ozone, considered a killer of virus in the nature, has been widely used by people for disinfection, sterilization, deodorization, disintoxication, storage, and bleaching thanks to its strong oxidablity.
And because of this, ozone should be adopted as a weapon in the global fight against COVID-19. It has three following attributes.
Full coverage. Ozone created by ozone generators or electrostatic air purifiers can reach every corner of the environment, which can overcome the problem that ultraviolet sterilization can only go straight up and down, leaving some places unsterilized.
High detergency. Oxidizing bacteria and virus is how ozone works, with no poisonous residue. On the contrary, the chemical disinfectant we use now is not only harmful to human body, but also will cause secondary population of poisonous residue. During the current epidemic, the overuse of disinfecting water has been a serious problem that we should pay attention to.
Convenience.Ozone can be produced by simple equipment. The equipment, large or small, can be used for a single room, a large public space, or public transportation modes such as buses, high-speed railways, ships and airplanes.
The effectiveness of ozone in treating bacteria and virus is not only related to its concentration, temperatures, humidity and exposure time, but also related to the strains of bacteria.
According to results of the experiment on how ozone kills SARS virus conducted by the national P3 laboratory headed by Professor Li Zelin, ozone is effective in killing the SARS virus inoculated on green monkey kidney cells, realizing a killing rate of 99.22%. The virus found in Wuhan and SARS virus both belong to the coronavirus. Researchers found that the novel coronavirus is 80% similar to the SARS virus in their genome sequences. It is reasonable to predict that ozone is equally effective in preventing and controlling the new coronavirus.
Ozone, though highly effective for sterilization and disinfection, will cause discomfort, or irritate mucous membranes, when it reaches a certain concentration level. Therefore, it is mainly used in unmanned environment.
If ozone can be used in a human environment to kill the new coronavirus and clean air, it will be a blessing to use it in crowded hospitals, factories, public spaces, closed public transportation, and indoor homes.
Whether ozone can take effect heavily depends on our ability to control its concentration levels. The volatile gas is easy to produce, but difficult to be controlled at a certain level, because of the cost of ozone sensors. Without the real-time test of sensors, it is out of the question to control its concentration.
If ozone can be controlled under a safe level by cheap and effective measures, ozone can be more easily used by people, which will lead to its use in human environment. Therefore, how to dramatically reduce the cost of ozone sensors is the challenge to be addressed at the moment.
Amid the epidemic, it is suggested that we can reasonably heighten standards for indoor ozone levels and try using ozone for disinfection and sterilization in human environment. Fortunately, Zhang Yue has donated ozone-generating purifiers to Huoshenshan Hospital and cubic hospitals, hoping this equipment can play a role in protecting medics lives and saving infected patients.
The relationship between ozone and microorganism demonstrates the exquisite balance on living bodies on earth. On the one hand, without the protection of the ozone layer, bacteria and virus cannot be found on earth, and on the other hand, ozone with strong oxidablity will kill bacteria and virus. Peoples knowledge of ozone is still far from enough. We should abandon the prejudice of ozone, the over vigilance of ozone, try to solve the puzzle of ozone, and fully explore the characteristics of ozone for human use. We must secure the help of ozone at the time of the new coronavirus epidemic. We must work together to make good use of ozone to defeat the epidemic.
Japan researchers say ozone effective in neutralising coronavirus
Reporting by Rocky Swift; Editing by Robert Birsel, www.reuters.comAugust 26, 2020
TOKYO (Reuters) - Japanese researchers said on Wednesday that low concentrations of ozone can neutralise coronavirus particles, potentially providing a way for hospitals to disinfect examination rooms and waiting areas.
Scientists at Fujita Health University told a news conference they had proven that ozone gas in concentrations of 0.05 to 0.1 parts per million (ppm), levels considered harmless to humans, could kill the virus.
The experiment used an ozone generator in a sealed chamber with a sample of coronavirus. The potency of the virus declined by more than 90% when subjected to low level ozone for 10 hours.
“Transmission of the novel coronavirus may be reduced by continuous, low-concentration ozone treatment, even in environments where people are present, using this kind of system,” said lead researcher Takayuki Murata.“We found it to be particularly effective in high-humidity conditions.”
Ozone, a type of oxygen molecule, is known to inactivate many pathogens, and previously experiments have shown that high concentrations, between 1-6 ppm, were effective against the coronavirus but potentially toxic to humans.
A recent study at the Georgia Institute of Technology showed that ozone may be effective in disinfecting gowns, goggles and other medical protective equipment.
Fujita Medical University Hospital, in Aichi prefecture central Japan, has installed ozone generators to reduce infection in waiting areas and patient rooms.
The university has also performed a clinical trial of Fujifilm Holdings Corps 4901.T Avigan drug on COVID-19 patients.
Official Expert Opinion of the International Scientific Committee of Ozone Therapy
Official Expert Opinion of the International Scientific Committee of Ozone Therapy (ISCO3).ISCO3/EPI/00/04 (March 14, 2020). Approved by ISCO3 on 13/03/2020. https://isco3.org/Potential use of ozone in SARS-CoV-2 / COVID-19 (pdf):
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Ozone: A Potential Oxidant for COVID-19 Virus (SARS-CoV-2)
The Journal of the International Ozone AssociationVolume 42, 2020Author: Tizaoui Chedly, College of Engineering, Swansea University, Swansea, SA1 8EN, United Kingdom
ConclusionsThrough molecular modeling, this study showed that ozone could be an effective oxidant against SARS-CoV-2. Ozone could attack the proteins and lipids of the virus’s spikes and envelope, thus destroying the integrity of the virus and inhibiting the mechanism by which it infects. Ozone could support the current effort in fighting COVID-19.Full Article read here: www.tandfonline.comOzone: A Potential Oxidant for COVID-19 Virus (SARS-CoV-2) (pdf):
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